Purpose : Anaphylactoid purpura, a common cause of vasculitis in children, usually involves the skin, gastrointestinal tract, jonit and kidney. The aim of this study is to provide a profile of clinical features of this disorder, as well as to investigate the prognostic significance of various clinical parameters which it depends on the involvement of kidney or relapse.
Method : This study included 80 patients with anaphylactoid purpura who had been admitted to the Department of Pediatrics of Wonkwang university hospital from Jan. 1, 1995 to Dec. 31, 1997. The presenting symptoms, associated disease, hematologic features and the abscence or prescence of renal involvement were studied in the patients retrospectively.
Results : The results were as the follows.
1. The male to female ratio was approximately 1.5:1.
2. The incidence according to age were 5 to 10 years of age in 48(60.0%), 10 to 15 years of age in 18(22.5%), and 1 to 5 years of age in 14(17.5%).
3. There were somewhat seasonal variations : Nov. to Dec. in 20(25.0%), Sep. to Oct. in 19(23.7%), March to April 18(22.5%), and in Jan. to Feb. in 12(15.0%)
4. The history of upper respiratory tract infections showed high incidence in the patients
with anaphylactoid purpura 58(72.5%).
5. The major clinical manifestations on admission showed skin lesions in 77(96.3%), gastrointestinal symptoms in 46(57.5%), joint symptoms in 42(50.5%), and renal manifestations in 2(2.5%).
6. Seventeen(21.3%) of 80 patients occurred renal disease in anaphylactoid purpura. There were no statist, cally significance of various clinical parameters which it depends on the renal involvement except the platelet level.
7. Eleven(13.8%) of 80 patients recurred. There were no significant relationships between the recurrence of anaphylactoid purpura and various clinical parameters.
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